Psychologist Says Antidepressants Are Just Fancy Placebos

Irving Kirsh aims to “explode the myth” of Prozac and its ilk, arguing that there’s little evidence that they actually work for most patients, by Carlin Flora; photograph by Jared Leeds From Discover Magazine Brain special issue; published online June 9, 2010.

Why is that some people respond very well to them and others don’t? Worse still is that some people are able to handle the side-effects of a trial-and-error treatment and others find the the side-effects so adverse that they refuse to try them again?